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Please use this identifier to cite or link to this item: http://hdl.handle.net/10400.5/483

Title: Body Composition and metabolic syndrome features in overweight and obese women
Authors: Rocha, Paulo Manuel Espadinha Pinheiro da
Advisor: Sardinha, Luis Fernando Cordeiro Bettencourt
Keywords: Adipose tissue
Body composition
Cardiovascular disease
Metabolic syndrome
Risk factors
Composição corporal
Doenças cardiovasculares
Factores de risco
Síndrome metabólica
Tecido adiposo
Issue Date: 16-Feb-2007
Abstract: This thesis sought to analyze the relationships between body composition markers and metabolic syndrome features in overweight and obese women, being structured in three scientific problems. The first scientific problem investigated the separate contributions of waist and hip circumference to proinflammatory and atherothrombotic metabolic syndrome disturbances. Associations of thigh adipose and muscle tissue compartments with metabolic features were also studied. For a given waist circumference, a larger hip circumference predicted a lower diabetogenic and atherothrombotic risk. Femoral-gluteal adipose tissue seems to mediate this protective role. The second problem studied the independent associations of abdominal and thigh adipose tissue compartments with metabolic syndrome clinical features. Contrarily to visceral adipose tissue, a larger thigh subcutaneous adipose tissue was related with a lower thrombotic and atherogenic risk. The last problem analyzed the independent relations of abdominal and thigh adipose tissue compartments with liver fat. The associations of proinflammatory and atherothrombotic risk factors with liver fat were also studied. Thigh subfascial adipose tissue was inversely associated with liver fat, suggesting that this thigh fat depot may play a protective role against ectopic liver fat storage. An abdominal obesity phenotype associated with a diabetogenic, inflammatory, and atherothrombotic metabolic profile may to contribute to liver lipotoxicity.
Description: Tese de Doutoramento em Motricidade Humana na especialidade de Saúde e Condição Física
URI: http://hdl.handle.net/10400.5/483
Appears in Collections:EXS - Teses de Doutoramento
BFMH - Teses de Doutoramento / Ph.D.Thesis

Files in This Item:

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PRocha_Resumo Alargado.pdfResumo alargado207.79 kBAdobe PDFView/Open
PRocha_Capa e indice Final.pdfCapa e índice final931.46 kBAdobe PDFView/Open
PRocha_Chapter 1.pdfIntrodução 704.93 kBAdobe PDFView/Open
PRocha_Chapter 2.pdfMetodologia228.61 kBAdobe PDFView/Open
PRocha_Chapter 3.pdfResultados224.36 kBAdobe PDFView/Open
PRocha_Chapter 4.pdfResultados217.28 kBAdobe PDFView/Open
PRocha_Chapter 5.pdfResultados187.84 kBAdobe PDFView/Open
PRocha_Chapter 6.pdfDiscussão183.66 kBAdobe PDFView/Open
PRocha_Chapter 7.pdfConclusão107.23 kBAdobe PDFView/Open
PRocha_Chapter 8.pdfAgradecimentos70.64 kBAdobe PDFView/Open
PRocha_Chapter 9.pdfSobre o autor110.95 kBAdobe PDFView/Open
PRocha_Chapter 10.pdfPublicações143.07 kBAdobe PDFView/Open
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