Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.5/7271
Título: Natural infection of synathropic rodent species Mus musculus and Rattus norvegicus by Leishmania infantum in Sesimbra and Sintra – Portugal
Autor: Helhazar, Marcos
Leitão, José
Duarte, Ana
Tavares, Luís
Fonseca, Isabel Pereira da
Palavras-chave: Leishmaniosis
Leishmania infantum
Mus musculus
Rattus norvegicus
Data: 8-Abr-2013
Editora: BioMed Central Ltd.
Citação: Helhazar, M., Leitão, J., Duarte, A., Tavares, L. & Fonseca, I.P. (2013). Natural infection of synathropic rodent species Mus musculus and Rattus norvegicus by Leishmania infantum in Sesimbra and Sintra – Portugal. Parasites and Vectors, 6:88, 1-6. doi:10.1186/1756-3305-6-88
Resumo: Background: Canine leishmaniosis caused by Leishmania infantum is a parasitic zoonotic disease transmitted by phlebotomine sandflies (Diptera: Psychodidae). Genus Phlebotomus is the biological vector in the Old World and Lutzomyia in the New World. The dog is the domestic reservoir host but other animals like the fox (Vulpes vulpes) and rodents are known to maintain the infection in both sylvatic and domestic cycles. Methods: To identify the role of synanthropic rodents Mus musculus and Rattus norvegicus as reservoir hosts for Leishmania infantum natural infection, 30 rodents were captured under a trap rodent control program in two private dog shelters from Sintra and Sesimbra, located in the Lisbon Metropolitan Area, known to be endemic for canine leishmaniosis in Portugal. Tissue samples were screened for the presence of Leishmania amastigotes by qPCR and parasitological analysis. Results: A total of 33.3% (9/27) of Mus musculus rodents revealed the presence of Leishmania spp. DNA while 29.6% (8/27) were positive in the parasitological analysis. Concerning Rattus norvegicus (n=3), one animal revealed infection only by parasitological analysis. Conclusions: Our results identified for the first time in Portugal the presence of Leishmania infection in both rodent species. As susceptible hosts, infected Mus musculus and Rattus norvegicus may increase the risk for dog and human infection in households and surrounding areas, enhancing the need for efficient rodent control measures in shelters and risk zones to prevent transmission of the infection.
Descrição: Articles in International Journals
Peer review: yes
URI: http://hdl.handle.net/10400.5/7271
DOI: 10.1186/1756-3305-6-88
Versão do Editor: http://www.parasitesandvectors.com/content/6/1/88
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CIISA - Artigos em revistas internacionais

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